SPIL-OVA launches proactive surveillance for zoonotic viruses to strengthen Africa’s pandemic preparedness

The Surveillance Platforms and Immunology for Zoonotic Viruses with Pandemic Potential in Africa (SPIL-OVA) programme has officially launched, marking a major step toward proactive pandemic preparedness on the continent. The initiative focuses on identifying and characterising high-risk viruses circulating in African bat populations before they spread to humans or domestic animals.

SPIL-OVA will collect bat samples from East, West, and Southern Africa and use advanced laboratory and computational techniques to analyse viral diversity and assess spillover risk. By comparing newly identified bat viruses with known human and animal pathogens, the programme will flag viruses with pandemic potential for further laboratory testing. Where a high likelihood of human infection is identified, prototype vaccine components—known as immunogens—will be designed to support rapid outbreak response.

Reflecting on the kick-off meeting, Prof Charles Sande described the programme as a milestone for African-led science, “It was a coming of age moment, where the continent’s scientific priorities were defined by Africans, led by Africans and managed by Africans.”

For Dr Constantinos Kurt Wibmer, the launch signalled the start of discovery-driven science: “SPIL-OVA kicked off a thrilling hunt for hidden viruses… decoding every fold and helix, spilling viral secrets one crystal blueprint at a time.”

The kick-off meeting brought partners together for in-depth planning and scientific exchange, setting the foundation for long-term collaboration. Dr Jinal Bhiman noted that the discussions highlighted the strength of the consortium, “The meeting was an excellent prelude to the next five years of collaboration as we drive next-generation innovation and strengthen Africa’s pandemic preparedness.”

Looking ahead, Dr Chinedu Ugwu emphasised the programme’s broader impact, “From elucidating Africa’s bat virome to creating immunogen libraries, we are building the foundations for future vaccines and global health resilience.”

By combining virus discovery, risk analysis, and vaccine preparedness, SPIL-OVA aims to create an early-warning system that shifts pandemic response in Africa from reactive to preventive.