Africa Pandemic Sciences Collaborative

Hosted by:
Science for Africa Foundation
03rd Riverside Drive, Nairobi, Kenya.

Research Area

Clinical research and clinical trials on epidemic and pandemic prone infections

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Lead Institution

Infectious Diseases Institute, Makerere University,
Uganda (Dr Christine Sekaggya-Wiltshire)

The Partners

  • Catholic University of Bukavu, Democratic Republic of the Congo (Professor Patrick de Marie Katoto),
  • Kibong’oto Infectious Diseases Hospital, Tanzania (Professor Stellah Mpagama),
  • University of Cape Town, South Africa (Professor Mario Denti)

Advancing Capacity for Early Phase Trials for Pandemics and Epidemics in Africa (ACCEPT-Africa)

The ACCEPT-Africa Consortium is an initiative focused on strengthening Africa's response to epidemic prone infectious diseases, particularly Mpox, Ebola and Marburg. This project aims to establish a robust clinical trial network across Uganda, Tanzania, Democratic Republic of Congo.

The consortium’s approach includes three main objectives:

  • To evaluate antiviral treatments through three clinical trials
  • To understand community perceptions, ethical considerations, and the feasibility of clinical trials in epidemic-prone areas; and
  • To build sustainable local research capacity by training scientists in pharmacokinetics, trial design, and bioethics.

The project will also assess community attitudes toward new treatments, ensuring that interventions are culturally sensitive and widely accepted. The consortium will contribute to improving Africa’s capacity to conduct early-phase trials for emerging infectious diseases, ultimately helping mitigate future health crises.