SHARPER Team Convened at the University of Cape Town, Attended the World Congress on Public Health, and Delivered Two Sessions that Promote Rights-Based and Population-Focused Health Research Benefit-Sharing

Annual Cross-Site Meeting: Reflecting, Strategising, and Strengthening Collaboration

From 10th to 12th September 2026, the SHARPER Project team convened at the University of Cape Town for its annual cross-site meeting, bringing together ten researchers and partners from across participating institutions to review progress, reflect on achievements, and strategically plan priorities for the year ahead.

The meeting provided an important platform for partners to assess ongoing activities across project sites, share experiences, discuss emerging challenges, and strengthen collaboration towards achieving SHARPER’s objectives of advancing ethical, rights-based, and population-focused approaches to health research.

Through constructive discussions and strategic planning sessions, the team reviewed implementation progress, identified opportunities for strengthening cross-site learning, and aligned future activities to ensure continued impact across research, policy, and practice. The meeting reinforced the value of collaborative approaches in addressing complex public health challenges and promoting research systems that prioritise ethics, equity, and meaningful benefits for populations.

Before the meeting, the SHARPER team participated in the World Congress on Public Health held between September 6-9, 2026, at the Cape Town International Convention Center, where the team contributed to global conversations on strengthening ethical and equitable approaches to health research.

Interactive Workshop and Role-Play, titled: If We Really Want Pandemic Preparedness, We Must Ensure Equity and Justice – The Role of Ethics Committees and Researchers in Promoting Population Benefits from Health Research

On 6th September 2026, at the 2026 World Congress on Public Health held in Cape Town, SHARPER Project organised an interactive workshop exploring the responsibilities of researchers, ethics committees, and health research stakeholders in ensuring that research generates meaningful benefits for populations.

The workshop brought together the expertise and leadership of SHARPER investigators and partners from different African institutions and public health networks, including representatives from the University of Cape Town, South Africa; University of Ibadan, Nigeria; Cameroon Bioethics Initiative, Cameroon; Tropical Institute for Community Health, Kenya; Kamuzu University, Malawi; and Afya na Haki, Uganda.

A central feature of the workshop was a mock Research Ethics Committee (REC) meeting through role-play involving the ethical review of a proposed artificial intelligence (AI)-guided diagnostic study for cardiomyopathy. The role-play simulated an ethics committee review process, allowing participants to identify practical ethical challenges related to AI-driven health research, conflicts of interest, technology ownership, and equitable access to research benefits.

The role-play involved a simulated REC meeting consisting of a chair, a committee member presenting the research protocol, an additional committee member raising ethical concerns, and audience volunteers participating as REC members. Through this approach, participants were encouraged to critically examine how ethics committees assess not only scientific validity and participant protection but also broader questions of justice and benefit sharing.

During the discussion, participants explored whether researchers and sponsors have responsibilities beyond conducting scientifically valid studies, particularly regarding access to successful interventions after research completion. The session examined the importance of developing proactive plans to ensure that communities contributing to research are not excluded from benefiting from resulting innovations.

Following the role-play, participants reflected on the ethical issues raised through an interactive audience engagement exercise using Mentimeter. Discussions focused on questions including whether participants were treated fairly, whether the research adequately addressed population benefits, and whether the protocol sufficiently considered equitable benefit sharing.

The lessons from the workshop reinforced the importance of integrating equity, justice, and accountability into health research governance. Participants reflected on how ethics committees can play a stronger role in ensuring that research conducted in African contexts contributes to sustainable health improvements and meaningful benefits for African populations.

Poster Presentation: Why Ethics, Human Rights, and Population Benefits Matter

Following the workshop, the SHARPER Project presented a poster exploring the critical importance of ethics, human rights, and population benefits in shaping responsible health research.

The presentation highlighted the need to move beyond traditional approaches to research ethics that primarily focus on protecting individual participants, towards broader considerations of justice, equity, accountability, and the fair distribution of benefits arising from research. The presentation emphasised that public health research should not only generate scientific knowledge but also contribute meaningfully to improving the wellbeing of populations, particularly communities that participate in research and contribute to the advancement of health innovations.

Drawing on SHARPER’s mission to strengthen healthcare and apply research for population health, ethics, and rights, the poster presentation stimulated discussions around how researchers, ethics committees, policymakers, and communities can work together to ensure that research outcomes translate into sustainable population benefits. It also provided an opportunity to engage conference participants on the role of ethical frameworks in addressing global health inequalities and ensuring that advances in health research are accessible, equitable, and socially responsive.

Ultimately, SHARPER Project’s activities at the World Congress on Public Health highlighted three important messages. Firstly, ethical health research must consider not only how research is conducted, but also who benefits from its outcomes. Secondly, human rights and equity must remain central to decisions about research design, governance, and implementation. Lastly, researchers, ethics committees, governments, regulating agencies and communities share responsibility for ensuring that health innovations translate into population benefits.

Through the interactive workshop and poster presentation, SHARPER created opportunities for critical reflection and dialogue on strengthening ethical research systems and ensuring that public health research better serves populations.

Cocktail at the University of Cape Town Leadership

At the conclusion of the annual meeting and World Congress activities, on 12th September 2026, the SHARPER Project team held a cocktail with the Deputy Vice-Chancellor of the University of Cape Town, and some UCT management staff at the All Africa House. The meeting provided an opportunity for the team to formally acknowledge the support and institutional environment that enabled the successful convening of SHARPER activities in UCT. Discussions during the cocktail visit reaffirmed the importance of strengthening partnerships, advancing collaborative research, and continuing efforts to promote ethical, equitable, and impactful approaches to public health research.

SHARPER Project is being implemented with the support of the Africa Pandemic Sciences Collaborative, a multi-year partnership between the Science for Africa Foundation, the Pandemic Sciences Institute at the University of Oxford, and the Mastercard Foundation.

Follow the SHARPER Project social media channels for updates on engagements focused on ensuring that health research delivers meaningful benefits for populations.

Written by Adams Adeshola, Communications Officer, SHARPER Project. 

From Kibong’oto Infectious Diseases Hospital to Tanzania Infectious Diseases Institute: A milestone for infectious disease preparedness in Tanzania and the continent

A century after its establishment as a tuberculosis (TB) sanatorium, Kibong’oto Infectious Diseases Hospital (KIDH) has reached a defining milestone in its history. After more than a decade of sustained investment in scientific expertise, research infrastructure, and institutional systems, KIDH has been elevated into the Tanzania Infectious Diseases Institute (TIDI), a significant step forward for Tanzania’s infectious disease preparedness.

On 24 July 2026, through a Government Gazette Notice No. 216 of 2026, the Government of Tanzania formally established TIDI. The new institute expands KIDH’s mandate beyond specialized clinical care to include a broader national role in infectious disease research, preparedness, rapid response, and scientific capacity development.

This significant milestone coincides with 100 years of TB services at Kibong’oto. From its origins as a TB sanatorium in 1926, the institution has evolved into a national institute positioned to address a wider range of infectious disease threats.

“The transition to TIDI represents the most significant transformation in Kibong’oto’s 100-year history. It broadens our role from specialised infectious-disease care to a national platform for research, surveillance, preparedness, training and innovation, while strengthening Tanzania’s contribution to regional and global health security.”

— Professor Stellah Mpagama, Director of Research Training and Innovations Tanzania Infectious Diseases Institute (TIDI)

Prof Stellah Mpagama at Tanzania Infectious Diseases Institute (TIDI)

This transformation reflects the changing health landscape in Tanzania and the wider East African region, where emerging and re-emerging infectious diseases continue to pose a growing risk. The establishment of TIDI represents an important step towards strengthening Tanzania’s ability to anticipate, investigate, and respond to future health threats. Strengthening national instituitions that can connect specialized clinical care with research, evidence generation, clinical trials and rapid response is increasingly important.

The transformation did not happen overnight

For more than a decade, KIDH has received sustained investment towards strengthening its technical, research, and administrative capacity. During this period, the institution developed specialized expertise in managing drug-resistant TB and other infectious diseases, expanded its outreach to underserved and marginalized communities, and strengthened its laboratory and research infrastructure.

The Kibong’oto Public Health Laboratory

KIDH also established the capacity to conduct Phase II and III clinical trials in TB and HIV, demonstrating its growing role as a centre for high-quality clinical research. These investments provided a strong foundation for the institution’s expanded mandate.

Intensive Care Unit Building

More recently, participation in the Advancing Capacity for Early Phase Trials for Pandemics and Epidemics in Africa (ACCEPT-Africa) consortium has supported the next stage of this journey. Through the consortium, KIDH/TIDI is strengthening its readiness to conduct early-phase clinical trials, including the development of Phase I capabilities, stronger clinical and research systems, and multidisciplinary research teams.

Collaboration with the Infectious Diseases Institute (IDI) at Makerere University, and other consortium partners has also created opportunities for technical learning, knowledge exchange, and regional collaboration. These partnerships are helping strengthen the capacity of African institutions to prepare for and respond to future epidemics and pandemics.

Additionally, investment in people has been central to KIDH’s transformation. The institution has supported the development of a growing generation of researchers and research leaders, including more than 25 MSc trainees, 19 PhD trainees, and 15 postdoctoral trainees. It has also developed seven research administration personnel and strengthened grant management and institutional governance.

“I was a PhD fellow in the ReMODEL training programme at TIDI, formerly KIDH, which was supported by EDCTP2. Through this programme, I networked and worked with several other consortia, including the Training Health Researchers in Vocational Excellence (ThRIVE-2) and the Application of Genomics and Modelling to the Control of Virus Pathogens in East Africa (GeMVi), the latter supported by NIHR. The programme strengthened my early-career research skills, including conceptual, technical and interpersonal skills in pathogen genomics, which have created a spillover effect into the ACCEPT-Africa consortium.”

— Dr. Shabani Mziray, Laboratory Scientist

Together, these investments have strengthened the expertise and systems needed to manage complex research programmes, attract competitive funding, and generate evidence that responds to Tanzania’s health priorities.

The impact of TIDI extends beyond the institution itself

For Tanzanian researchers and young scientists, the revised institutional mandate creates new opportunities to build careers in advanced infectious disease research while contributing to solutions for health challenges facing their own communities.

For patients and communities, the institute offers the potential for greater access to specialized expertise and research-informed care. It also provides a stronger platform for evidence generated in Tanzania to inform responses to the health threats affecting Tanzanian communities.

The transformation into the Tanzania Infectious Diseases Institute (TIDI) is more than a change of name. From its beginnings as a TB sanatorium in 1926 to a national infectious diseases institute a century later, TIDI’s journey demonstrates what sustained investment in people, infrastructure, institutions and partnerships can achieve over time. For the ACCEPT-Africa consortium, this milestone provides a tangible example of how investments in clinical trial readiness and scientific capacity can contribute to lasting institutional development, while creating opportunities to strengthen Tanzania’s research ecosystem and its contribution to regional pandemic preparedness.

As TIDI begins this new chapter, it is better positioned to advance clinical and infectious disease research, generate evidence, develop scientific leaders and strengthen Tanzania’s capacity to respond to emerging health threats. The next phase will focus on translating this expanded mandate into stronger research infrastructure, early-phase clinical research capability and new opportunities for collaboration. Together, TIDI and ACCEPT-Africa can help build a stronger platform for pandemic research in Tanzania and across Africa, bringing researchers, institutions, policymakers and partners together to share expertise, deepen collaboration and contribute to a more resilient continental research ecosystem.

Tanzania Infectious Diseases Institute’s (TIDI) Radiology building

Written by Onai Yambazi, Communications Officer, ACCEPT-Africa consortium

Three Consortia, One Mandate: Inside Uganda’s EPSILONs Unified Pandemic Preparedness and Response System

The lull between outbreaks is often defined by a quiet, dangerous erosion: trained personnel move on, specialized laboratories pivot, and institutional memory fades. When the next virus occurs, Africa’s scientific community is forced to rebuild its response efforts from scratch.

On July 31, 2026, inside the Sande McKinnell Centre at Makerere University’s Infectious Diseases Institute (IDI) three Ugandan-based Epidemic and Pandemic Sciences Innovation and Leadership Networks (EPSILONs) consortia committed to a different approach: build connections before the next outbreak, not during it.

The Uganda EPSILON Mini-Launch brought together: Advancing Capacity for Early Phase Trials for Pandemics and Epidemics in Africa (ACCEPT-Africa), Prevention and Response to Emerging viruses with Pandemic potential in Africa Epsilon (PREPARE) and Strengthening Health systems capacity in Africa for Pandemic Equity and Responsiveness (SHARPER) – three consortia working across different but interconnected areas of pandemic preparedness under the Africa Pandemic Sciences Collaborative. Their meeting marked a shift from parallel efforts towards greater collaboration and long-term capacity building.

Beyond Parallel Silos

Each consortium brings a distinct capability to Uganda’s pandemic preparedness.

ACCEPT-Africa focuses on clinical trials and medical countermeasures, building the capacity to design and conduct early-phase clinical trials in Africa. PREPARE is focused on an early vaccine and diagnostic development for priority pathogens

 helping generate timely evidence on emerging pathogens. SHARPER focuses on the social, ethical and community dimensions that underpin effective research and response.

“ACCEPT-Africa was built to move fast when speed matters most,” said Dr Christine Sekaggya-Wiltshire, who leads the consortia. “But no single network can prepare a country alone. Standing alongside SHARPER and PREPARE today means we can pool our strengths, share what each of us has learned, and respond as one system instead of three.”

 “Preparedness cannot live in silos,” added Dr Andrew Kambugu, IDI’s Executive Director. “Today’s Mini-Launch is IDI’s commitment to a Uganda where our pandemic science networks plan together, train together, and respond together, long before the next outbreak begins.”

The gathering brought together representatives from Uganda’s Ministry of Health, Makerere University College of Health Sciences, Africa CDC, the Science for Africa Foundation and research institutions, reflecting the range of actors needed to translate scientific capacity into effective preparedness.

The Case for Each Other

The morning’s presentations showed why the three consortia need each other.

Dr Daniel Kiiza laid out ACCEPT-Africa’s ambition to build a sustainable pool of independent African research scientists capable of designing and running early-phase trials rather than Africa remaining a site where products developed elsewhere are simply tested.

Dr Joyce Namulondo described PREPARE’s push to close the gap between an outbreak starting and a pathogen being understood. Using influenza as an example, she highlighted the role of genomic surveillance in tracking rapidly evolving viruses and generating evidence that can inform vaccine development.

Nimrod Muhumuza presented SHARPER’s case that no amount of laboratory excellence survives contact with a community that does not trust the response. The consortium’s guiding line was that researchers must not simply take science to communities but build science with them.

Together, the presentations made a simple point: detecting a pathogen, developing a medical response, and ensuring that communities can participate in and benefit from that response are not separate challenges. They are parts of the same pandemic preparedness and response system.

Building Science with the Community

The afternoon’s panel discussions moved quickly past administrative goals to address the stark realities of field deployment. When asked how response teams can navigate mistrust such as the tragic attacks on Ebola treatment units seen in neighbouring DRC during the 2026 outbreak, the consensus was unequivocal: technical excellence fails if community trust is absent.

Dr Moses Mulumba spoke about SHARPER’s focus on an “Afrocentric” approach to research, including examining whether research standards developed elsewhere adequately reflect African contexts and values. The approach also asks a broader question: whether communities are merely sources of data or participants who should experience meaningful benefits from the research.

Dr Christine Sekaggya-Wiltshire put it plainly: “We go beyond just the clinical trials; we build synergies with communities to understand their perceptions towards the work we are doing.”

Empowering Tomorrow’s Science Leaders

Central to the Africa Pandemic Sciences Collaborative’s mandate is ensuring that early-career researchers do not remain in administrative shadows. To operationalize this, Dr Sekaggya described ACCEPT-Africa’s Catalyst Groups in pharmacokinetics, clinical trials, bio-ethics and behavioral science, where junior scientists apply for grants under senior mentorship rather than waiting years to lead their first study.

Dr. Linda Murungi, Program Manager for the Africa Pandemic Sciences Collaborative, widened the definition of capacity building further. “It is not only about scientists,” she reminded the room, “but also the finance officers, grants managers and policy specialists who make African-led research possible. This institutional infrastructure may be less visible, but without it, no scientific breakthrough can survive.”

As the mini-launch concluded in Kampala, the significance of bringing the three consortia together was becoming clearer. Uganda’s pandemic preparedness does not depend on any single laboratory, research network or discipline. It depends on whether those capabilities can connect when they are needed.

SHARPER communication officer wins Best Oral Presentation Award at International Pandemic Conference 2026

Adams Adeshola, an early-career professional serving as the Communication Officer with the Strengthening Health Systems Capacity for Pandemic Equity and Responsiveness (SHARPER) project, won the Best Oral Presentation Award in the Ethics and Context category at the International Pandemic Sciences Conference in Singapore, held from 1–3 July 2026.

Adeshola’s presentation, titled Decolonising Research Ethics in Africa through Indigenous Language Institutionalisation: A Case Study of the Yoruba Language, was well received not only because of the relevance of the topic but also for his confident delivery. He argued that the informed consent process is often flawed, particularly when research involves complex medical terminology. He recommended that the use of indigenous African languages, such as Yoruba, which is widely spoken in south-west Nigeria, can improve participants’ understanding of research, foster trust between researchers and communities, and strengthen public engagement during disease outbreaks and pandemics. His presentation challenged conventional approaches to research ethics by demonstrating that effective communication is not merely a supporting component of public health but a critical pillar of ethical research, community participation, and pandemic preparedness.

Adeshola’s journey to the international stage began in January 2026 when the Pandemic Sciences Institute issued a call for abstracts for its annual conference. He submitted an abstract that was selected for oral presentation, and a bursary provided by the organisers enabled him to participate in the global event.

A graduate of the University of Ibadan, Adeshola holds a master’s degree in Linguistics and Languages. As SHARPER’s Communication Officer, he attended the conference to reinforce the project’s commitment to promoting ethical and community-centred research in Africa. His recognition marks a significant milestone for interdisciplinary scholarship, highlighting the growing importance of communication and the humanities in shaping research ethics and strengthening pandemic preparedness.

The three-day conference attracted leading researchers, policymakers, public health professionals and innovators from around the world to discuss some of the most pressing issues in pandemic sciences. Discussions covered a wide range of thematic areas, including Ethics and Context, Data, Analytics and Artificial Intelligence, Vaccines and Immunology, Diagnostics and Treatment, Pathogen Biology and Emerging Threats, and Policy and Governance.

Reflecting on receiving the award, Adeshola said:

“As the award presentation session was about to begin, I had taken out my phone simply to record the moment for those who would be recognised. So, when I heard my name called, I was overwhelmed with gratitude. To me, this award means far more than recognition for a presentation. It reaffirms my belief that ‘your background should never limit your future.’

As someone from the humanities, I know many young Africans believe that global health is reserved for those in the biomedical sciences. This experience, however, proves otherwise. Receiving recognition on a global stage affirms that communication, language, and other fields are not peripheral to global health; they are essential to building trust, strengthening research ethics, and improving pandemic preparedness. This award gives me even more confidence in the path I have chosen and inspires me to continue producing research that connects science with society. Above all, I hope it inspires other young people, especially those in the humanities, to believe that their voices matter and that they, too, belong on the global stage.”

Written by Prof Ademola Ajuwon, Principal Investigator of the SHARPER Consortium

The 2026 Ebola Outbreak: Why African Scientific Leadership and Collaboration Matter

The 2026 Ebola outbreak originating in the Democratic Republic of the Congo (DRC) represents a significant regional and global public health concern and highlights the critical role of surveillance, preparedness, scientific leadership, and regional collaboration in responding to epidemic threats.

 

SITUATIONAL OVERVIEW

In May 2026, health authorities in the DRC confirmed an outbreak of Ebola disease caused by the Bundibugyo strain of the virus in Ituri Province in the country’s northeast. Cases have since expanded to North and South Kivu provinces, and have also been reported in neighbouring Uganda, prompting heightened regional surveillance and preparedness efforts.

The World Health Organization (WHO) subsequently declared the outbreak a Public Health Emergency of International Concern (PHEIC), citing a growing number of reported infections in affected areas, the potential for cross-border spread, and the complex humanitarian and security conditions affecting response efforts in eastern DRC. The declaration is intended to strengthen international coordination and support for outbreak control measures.

As of 11 June 2026, 695 confirmed cases and 138 confirmed deaths had been officially reported in the DRC and Uganda. Health authorities are also investigating additional suspected cases as part of routine outbreak surveillance and case finding.  While the outbreak is unfolding in a context marked by population displacement, insecurity, misinformation, and limited humanitarian access in some affected areas, national authorities, researchers, and regional partners continue to deploy surveillance, diagnostic, and response measures to detect cases, interrupt transmission, and guide public health action.

The Bundibugyo strain presents particular challenges because no approved vaccines or specific treatments currently exist for this strain of Ebola virus. The outbreak therefore underscores the urgent need to strengthen Africa’s preparedness and response systems, accelerate research and development efforts, and expand equitable access to diagnostics, therapeutics, and outbreak response infrastructure.

At the same time, the response is also demonstrating Africa’s growing scientific leadership and the strengthening of African research ecosystems, public health institutions, and collaborative preparedness networks.

This is why the Africa Pandemic Sciences Collaborative exists. It aims to strengthen African-led research and institutions to enable them to conduct world-class, innovative research, and translate findings into impactful, locally relevant solutions that contribute to shaping and strengthening pandemic response and resilience and, ultimately, benefiting the continent’s health ecosystem for future generations.

The Africa Pandemic Sciences Collaborative stands in solidarity with affected communities and expresses its sincere appreciation to frontline healthcare workers, researchers, surveillance officers, laboratory teams, community health workers, and local leaders working tirelessly to contain the outbreak and protect lives. It is also committed to working with relevant health authorities and partners to effectively respond to this current outbreak.

 

THE COLLABORATIVE RESPONSE

Across the Collaborative’s Epidemic and Pandemic Science Innovation and Leadership Networks (EPSILONs), researchers and partners are actively supporting outbreak response and mitigation efforts spanning therapeutics, diagnostics, disease surveillance, clinical research, modelling, behavioural science, and community engagement.

In the DRC, researchers from our ACCEPT-Africa consortium are on the frontlines leading efforts with relevant health authorities and teams to identify cases, contain the spread of the virus, and find preventive and curative solutions to the outbreak. Specifically, we applaud the work led by Prof Placide Mbala and other colleagues at the Institut National de Recherche Biomédicale (INRB), Kinshasa – DRC, who played a leading role in identifying the Bundibugyo strain. Now that the specific pathogen is identified, they continue to support diagnostics expansion, setting up clinical trials for available candidate treatment, and studying the genetic makeup of the circulating strain of Ebola.

In Uganda, researchers from the ACCEPT-Africa and PREPARE consortia are supporting the national Scientific Advisory Group and helping strengthen regulatory readiness and emergency-use treatment protocols. Some priority drugs have been identified, and these are being fast-tracked for approval. Additionally, the team is drafting training materials for healthcare workers administering experimental treatments. Once approved, the bulk of the work will be around tracking patient outcomes. In addition, researchers at the Uganda Virus Research Institute (UVRI) are working with the Ministry of Health to strengthen near-point-of-care diagnostic systems using innovative Loop-Mediated Isothermal Amplification (LAMP)-based technologies to improve rapid detection capacity. LAMP is a rapid, highly sensitive molecular diagnostic technique that is portable and cost-effective used to detect specific DNA or RNA sequences in clinics or remote field work settings.

Despite these noble efforts, teams from both countries continue to face major challenges. These include shortages of rapid diagnostic tests, laboratory consumables, infection prevention supplies, and decentralized testing systems, alongside urgent needs for stronger disease modelling, community engagement interventions, clinical trial infrastructure, and biobanking systems to support both immediate response efforts and long-term preparedness.

With a combined ecosystem comprising of more than 40 lead researchers, the Collaborative network has consulted with the EPSILON PI’s in both countries and have proposed a range of coordinated scientific and operational interventions to support the Ebola outbreak response across affected countries. These include support for epidemiological and economic modelling through the CLEAR-Africa consortium to help optimise resource allocation and response planning in the DRC and Uganda, alongside adaptation of community education and prevention materials developed by the University of Ibadan to support locally relevant public health communication. The PREPARE consortium is also contributing diagnostic innovation through development and validation of surveillance and diagnostic platforms for zoonotic and epidemic-prone diseases, while the SPIL-OVA consortium is exploring the use of archived outbreak samples to support rapid diagnostic development and monoclonal antibody research targeting the Bundibugyo strain. Together, these efforts reflect the Collaborative’s interdisciplinary approach to strengthening diagnostics, surveillance, modelling, community engagement, and long-term epidemic preparedness across Africa.

Meanwhile, additional preparedness efforts are ongoing across our partner institutions in Liberia, Burkina Faso, Ghana, Mali, Kenya, and other countries through surveillance strengthening, laboratory readiness, traveller screening systems, risk communication and community engagement (RCCE), and cross-border preparedness activities.

 

URGENT PRIORITIES FOR RESPONSE AND PREPAREDNESS

The Collaborative has set aside some financial support, outside of the primary grants awarded to the research consortia, towards rapid response and preparedness efforts. The allocation of these resources will target four priority areas identified through consideration of the current outbreak dynamics, partner consultations, broader Ebola response experience, and lessons from previous epidemics.

1. Addressing diagnostic and laboratory gaps

Rapid diagnosis remains essential to early intervention, interrupting transmission chains and strengthening outbreak containment. However, both the DRC and Uganda continue to face shortages of rapid diagnostic tests, laboratory consumables, infection prevention supplies, and decentralized testing systems. There is a need to expand diagnostics to the affected communities using near-point-of-care diagnostic solutions that are sensitive to the Bundibugyo strain, to enable early medical care for cases and contact tracing. Additionally, despite the lack of reported cases in at-risk neighbouring countries, the deployment of diagnostic equipment across the region will enable the active tracking of suspected cases, leading to the containment of the virus.

2. Strengthening disease modelling and epidemic intelligence

Real-time modelling, analytics, and epidemic intelligence remain critical for guiding outbreak response operations, forecasting transmission dynamics, optimising resource allocation, and informing public health decision-making.

Collaborative partners have identified an urgent need to strengthen disease modelling and epidemic intelligence systems to support more effective outbreak response and preparedness efforts. Priority areas include enhanced epidemiological and economic modelling, integrated outbreak analytics, real-time data sharing, cross-border surveillance coordination, and decision-support tools to help Ministries of Health and response agencies make faster, evidence-based decisions during the outbreak.

3. Expanding One Health surveillance and animal sampling

The recurrence of Ebola outbreaks in similar geographic regions has reinforced the importance of strengthening One Health approaches that integrate human, animal, and environmental health systems. Researchers in the DRC have highlighted the urgent need to expand animal sampling and zoonotic surveillance, investigate potential spillover events, strengthen genomic sequencing and ecological monitoring systems, and improve understanding of environmental drivers of transmission, recognizing that stronger One Health surveillance will be essential not only for controlling the current outbreak, but also for preventing and anticipating future epidemic threats emerging at the human-animal-environment interface.

BUILDING AFRICA’S FUTURE PANDEMIC RESILIENCE

The current Ebola outbreak is a reminder that preparedness cannot begin when outbreaks start. Sustainable epidemic resilience requires long-term investment in African scientific leadership, research institutions, public health systems, skilled workforces, trusted community engagement systems, and regional collaboration.

Through its network of EPSILONs, the Africa Pandemic Sciences Collaborative is supporting interdisciplinary research, workforce development, diagnostics innovation, therapeutics research, modelling systems, behavioural science, and One Health preparedness approaches across the continent.

Importantly, Africa’s future preparedness will depend not only on infrastructure and technology, but also on people. Developing and retaining the next generation of African scientists, clinicians, laboratory experts, epidemiologists, public health leaders, and data scientists will be critical to ensuring long-term resilience.

Disease outbreaks do not respect borders – and preparedness cannot stop at them. Sustained investment in African-led science and collaborative preparedness systems is therefore essential for the continent’s future and the global health security.

Preparedness is built between outbreaks – not during them.

 

CALL FOR PARTNERSHIP AND SUPPORT

We are ready to work together with governments, funders, research institutions, development partners, industry, and regional organizations to support:

  • Equitable access to diagnostics, treatments, and outbreak countermeasures
  • African-led research and preparedness systems
  • Disease surveillance, modelling, and laboratory strengthening
  • One Health and zoonotic surveillance systems
  • Long-term workforce development and scientific leadership

The current outbreak is not only a response challenge. It is an opportunity to strengthen the systems, partnerships, and scientific ecosystems needed to protect Africa, and the world, from future epidemic and pandemic threats.

For enquiries regarding partnership opportunities, or more information on our work relating to the current Ebola outbreak, please email: [email protected]

SHARPER Project Features in Capacity Building Training for Early-Career Researchers at the University of Ibadan, Nigeria

The Strengthening Health Systems Capacity in Africa for Pandemic Equity and Responsiveness (SHARPER) Project featured in a capacity strengthening programme at the University of Ibadan (UI) for approximately 400 newly recruited lecturers. Organized by the Research Management Office (RMO) of the university, the programme was designed to support the professional development and integration of the Early-Career Researchers (ECR) into the university system. It is also a part of efforts to strengthen the institution’s human resource capacity and reinforce its commitment to fulfilling its vision to be a world class institution for academic excellence geared towards meeting societal needs.

To foster effective facilitator-participant interaction, the workshop was delivered to participants in two batches. While the first batch of participants were trained from 4th to 6th May, the second was held between 1st and 3rd June 2026. During these programmes, several key aspects of academic life and institutional practice were covered. The sessions focused on the social responsibilities of academics, the opportunities and challenges associated with scholarship, promotion guidelines, work-life balance, mentorship and career advancement strategies.

At the training, Prof. Ademola Ajuwon, the  Principal Investigator of the SHARPER Project, delivered an insightful lecture on grant writing and research strategies. He provided participants with practical tips on how to search and win grants, developing competitive proposals, and maintaining ethical and professional standards in research.

Speaking on the importance of research grants in academic career development, Prof. Ajuwon introduced participants to the SHARPER Project and the opportunities it offers for ECR.  He explained that the project is a six-year socio-behavioural science research initiative focused on strengthening health systems capacity, pandemic preparedness and responsiveness, research benefit-sharing, and the promotion of African values in research ethics.

He highlighted that the SHARPER Project would provide three categories of research support annually across its six partner institutions, namely the College of Medicine, University of Ibadan, Nigeria; University of Cape Town, South Africa; Tropical Institute of Community Health, Kenya; Afya na Haki, Uganda; Kamuzu University of Health Sciences, Malawi; and the Cameroon Bioethics Initiative, Cameroon. The University of Ibadan serves as the lead institution for the project.

According to Prof. Ajuwon, the project’s Research Innovation Grants will offer up to $40,000, while the Catalyst Awards will provide up to $15,000 in funding. In addition, the Exchange Fellowships valued at up to $10,000 will be available to support collaborative learning and research exposure across partner institutions. He encouraged the participants to monitor the project’s social media platforms, particularly Facebook and LinkedIn, for upcoming Calls for Applications (CFAs). He also emphasised the project’s commitment to promoting inclusivity and equity in research participation, noting that women and applicants under 35 would receive priority consideration during the selection process.

While specific thematic priorities will be detailed in future calls, Prof. Ajuwon explained that the project’s major research areas include pandemic preparedness and responsiveness, research benefit-sharing, and African-centred approaches to research ethics and governance.

The announcement was enthusiastically received by participants, many of whom described the initiative as a important opportunity to strengthen the capacity of ECR expand access to funding opportunities, and improve female representation in research and global health discourse.

SHARPER is supported by the Africa Pandemic Sciences Collaborative. The Collaborative seeks to mentor, nurture, and equip an emerging generation of young African scientists and researchers to address current and future health challenges, contribute to strengthening the continent’s health ecosystem and pandemic preparedness and response capabilities, and to create pathways to dignified and fulfilling careers in pandemic sciences. The Collaborative is a multi-year partnership between the Science for Africa Foundation (SFA Foundation), the Pandemic Sciences Institute (PSI) at the University of Oxford, and the Mastercard Foundation.

As the training session drew to a close, participants engaged actively in discussions, asking questions, seeking clarification, and sharing reflections on the opportunities presented through the SHARPER Project. The interactive session provided Prof. Ademola Ajuwon with an opportunity to further engage the early-career academics on research development, grant competitiveness, and the broader vision of strengthening African-led research systems.

Going forward, the SHARPER Project remains committed to sustained stakeholder engagement through various communication and knowledge-sharing platforms. These efforts are aimed at ensuring wider visibility for the project, deepening awareness of its objectives, and advancing conversations around research benefit-sharing, pandemic preparedness and responsiveness, and ethical, African-centred approaches to research and global health governance.

Written by Adams Adeshola

Four EPSILON Consortia Launch at UCT to Strengthen Pandemic Preparedness in Africa

On Thursday, 21 May, the Institute of Infectious Disease and Molecular Medicine (IDM) at the University of Cape Town (UCT), South Africa, hosted the soft launch of four consortia funded by the Africa Pandemic Sciences Collaborative through a partnership between the Science for Africa Foundation, the University of Oxford’s Pandemic Sciences Institute, and Mastercard Foundation. Beyond supporting research, this collaboration also invests in strengthening the pandemic sciences ecosystem across the continent.

In total, seven Epidemic and Pandemic Sciences Innovation and Leadership Networks (EPSILONs) have been funded, each led by African scientists and designed to create a network of excellence in epidemic and pandemic sciences. The launch focused on the four consortia in which UCT is either the lead or a partner institution, spanning 11 African countries: Cameroon, Democratic Republic of the Congo (DRC), Ghana, Kenya, Malawi, Nigeria, Senegal, Tanzania, Uganda, Zimbabwe, and South Africa.

Opening remarks were delivered by Professor Wendy Burgers, Deputy Director of IDM, who reflected on the current lack of outbreak preparedness and the unequal global research landscape. Referring to discussions at the World Health Assembly and ongoing outbreaks such as Ebola in the DRC, she highlighted the need for African-led pandemic science and stronger collaboration across the continent.

Christina Pather from the Research Support Enterprise described the launch as “a step towards a stronger, more equitable and more resilient African research ecosystem”, while celebrating UCT’s participation in four of the seven funded projects and the interdisciplinary collaboration this represents.

The first consortium presented was the Consortium for Leadership of Epidemiological-economic Analysis for epidemic Response in Africa (CLEAR-Africa), led by Professor Sheetal Silal. CLEAR-Africa aims to strengthen preparedness for future pandemics by developing models that consider not only disease transmission and health outcomes, but also the social and economic consequences of public health responses. The consortium seeks to address the current modelling skills gap by training African researchers to lead and adapt epidemiological-economic models locally, ensuring that future outbreak responses are informed by both health and economic realities.

Associate Professor Jinal Bhiman then presented Surveillance Platforms and ImmunoLOgy for zoonotic Viruses with pandemic potential in Africa (SPIL-OVA), a consortium working at the human-animal interface to better understand zoonotic threats. SPIL-OVA focuses on identifying viruses with spillover potential circulating in African bat populations, recognised reservoirs of several emerging infections. Through multiple research work packages, the consortium aims to build knowledge about animal viral diversity, strengthen surveillance systems and support diverse leadership and scientific expertise across the continent.

Strengthening Health systems capacity in Africa for Pandemic Equity and Responsiveness (SHARPER) was presented by Professor Leslie London, representing one of the consortium partners. SHARPER seeks to transform how research is conducted and used in Africa by analysing the current policy and research landscape and identifying opportunities for change. The consortium will develop new tools, courses and academic outputs while placing equity, African values and human rights at the centre of pandemic preparedness and response, so as to ensure health research benefits populations and not only participants.

The final consortium presented was Advancing Capacity for Early Phase Trials for Pandemics and Epidemics in Africa (ACCEPT-Africa), presented by Dr Daniel Kiiza and Professor Paolo Denti. ACCEPT-Africa aims to strengthen early-phase clinical trial infrastructure across the continent, enabling trials, protocol development, and pharmacokinetic analysis to be conducted locally. The consortium also focuses on training researchers and laboratory teams so that future clinical research can be led within Africa and better reflect the populations it seeks to serve.

In their closing remarks, Angie Kerubo Mugisha and Dr Linda Murungi from the Africa Pandemic Sciences Collaborative, highlighted the importance of collaboration and thanked the principal investigators for their commitment to strengthening preparedness for future epidemics and pandemics. They reminded the audience that scientific knowledge should not remain within institutions but should reach communities and create impact at individual, institutional and systemic levels.

The launch concluded with a networking reception, bringing together students, researchers, partners, and consortium members. Earlier in the event, Professor Burgers reminded the audience that “Africa doesn’t lack talent; there has been a structural gap that has prevented the continent from working together.” The EPSILON programme seeks to address this gap by strengthening collaboration, leadership and scientific excellence across Africa.

Written by Elisabet Marti Coma-Cros and appeared HERE originally.  

Consortium leads visit Brown University Pandemic Centre for a Research Management Exchange

Scientists and researchers from the Africa Pandemic Sciences Collaborative network recently travelled to Providence for a high-level exchange with the Brown University Pandemic Center, marking a major step forward in strengthening pandemic preparedness and health security across Africa.  

The visit convened African research leaders alongside global partners to examine the practical architecture of research ecosystems focusing on governance, bio-surveillance, and translating science into policy action before the next health threat emerges.  

The exchange drew on the work of several active consortia within the EPSILON network, each contributing a distinct dimension to the broader challenge of building resilient health security systems on the continent. The delegation to Brown University included: 

  • Prof Sheetal Silal, Principal Investigator of the CLEAR-Africa Consortium, which strengthens evidence-based decision-making through epidemiological and economic analysis for epidemic response;  
  • Prof Ademola Ajuwon, who leads the SHARPER Consortium, focused on advancing ethical research systems and equitable access to the benefits of research across African health systems;  
  • Prof Seydou Doumbia, lead of the SCGRA Consortium, which builds collaborative capacity in genomic surveillance, emerging pathogens, and climate-health interactions; and  
  • Allen Mukhwana, Head of Programmes for Strengthening Science Ecosystems at the Science for Africa Foundation. 

Redefining Institutional Architecture: Core Takeaways 

The visit surfaced four main operational insights that directly inform EPSILON’s research management and translation agenda. 

First, The Brown Pandemic Center operates as a university-wide platform rather than a siloed department. Crucially, the Center maintains a strict separation between evidence synthesis and political advocacy – a structural principle that protects scientific credibility while ensuring research remains relevant to policy actors. 

 The delegation also examined the Boston University BEACON Project, which demonstrates that research translation must be a core, funded institutional function rather than an afterthought. BEACON uses hybrid AI-human workflows to triage hundreds of daily informal public health signals — including emerging Lassa fever trends in Nigeria — verifying them through expert review to deliver real-time, actionable intelligence. 

 A third lesson centred on institutionalising what practitioners call “boundary-spanners”: researchers embedded enough in government decision-making to be useful but anchored firmly enough in universities to retain scientific independence. Mechanisms such as academic time-buyouts and funded fellowships make this a sustainable professional track, not an informal arrangement dependent on individual goodwill. 

 Finally, the delegation examined Brown’s community engagement model, in which community partners and faculty co-lead funding applications with equal budget allocations. This provides a concrete institutional template for SHARPER’s objective of shifting research benefit-sharing from individual to community scale. 

 A Strategic Roadmap for Africa 

Unlike Northern pandemic centres anchored in a single workforce, EPSILON’s advantage lies in orchestrating a distributed, multi-country intelligence system across fragmented policy environments. Moving forward, the network is prioritizing a phased implementation strategy: 

In the near term, the priority is to pilot rapid translation and epidemic intelligence units within select EPSILON hubs, and to co-develop a modular research translation toolkit that can be adapted across different country contexts. 

 Over the medium term, the network aims to establish a centralised research intelligence layer linked directly to the Africa CDC and national public health institutes, creating structured pathways for scientific findings to reach and inform policy decisions. 

 The longer-term ambition is to secure diversified, platform-style funding — separate from short-cycle project grants — to sustain a continent-scale pandemic science synthesis platform capable of responding to health threats as they emerge, not after they have arrived. 

 Generating scientific knowledge is necessary but not sufficient. Translating that knowledge into decisions that protect lives requires the governance frameworks, institutional partnerships, and policy-facing infrastructure to act on it — at speed, and at scale. The Brown University visit brought that infrastructure into sharper focus for the EPSILON network. 

Read the full report here: Learning Visit Report: Brown University Pandemic Centre & BEACON Project

Building together, moving forward

In the first week of March 2026, program management representatives from the three Africa Pandemic Sciences Collaborative partners – the Science for Africa Foundation, the Pandemic Sciences Institute at the University of Oxford, and the Mastercard Foundation – convened in Nairobi for a strategic alignment workshop.

Over the past two years, the Collaborative has made significant progress toward its vision of strengthening Africa’s pandemic preparedness capacity. Seven EPSILON research consortia are now active across the continent, bringing together over 30 African universities and research institutions to advance novel research in pandemic and epidemic preparedness. As our partnership has grown and evolved, we came together to reflect on what is working, sharpen how we collaborate, and build a stronger foundation for the next phase of delivery. To this end, the Mastercard Foundation engaged CoCreative – an organisation experienced in supporting large-scale multi-partner collaboratives – to help design and facilitate this process.

It was a fun-filled week of deep collaboration, shared vision and renewed energy around one of the most important missions on the continent – strengthening Africa’s pandemic resilience and building an African-led science and innovation ecosystem. When you are co-creating a continent-wide research ecosystem across diverse countries, cultures and contexts, moments of intentional alignment are essential.

Together, we reflected on the significant progress we have made. At the heart of this work is the emerging generation of African scientists, innovators and health leaders who will shape the continent’s scientific future. Our role is to create the conditions for them to thrive, lead and deliver solutions – multiplying opportunities across biotechnology, epidemiology, data science and beyond.

Weeks like this remind us why co-creation and collaboration matter. We are building something important together, and this week strengthened the foundation that will carry us forward. We leave with sharper clarity on how to work together, and deeper commitment to the scientists and institutions whose work will define Africa’s pandemic preparedness for generations to come.

MEAL leads convene to strengthen alignment across the Collaborative

24-27 November 2025 | Lagos, Nigeria

The Africa Pandemic Sciences Collaborative exists to strengthen Africa’s capacity for pandemic preparedness through evidence-driven decision-making, strong institutions, and learning systems that respond to context. This was a central message highlighted over four days of a workshop that recently took place in Lagos, Nigeria.

Monitoring, Evaluation, Accountability and Learning (MEAL) leads from all seven EPSILON consortia met in Lagos for a four-day onboarding workshop aimed at strengthening alignment, sharpening shared understanding, and establishing a unified approach to monitoring, evaluation, accountability and learning across the Collaborative.

Co-hosted by SHARPER and SPIL-OVA consortia based at the University of Ibadan and Redeemer’s University respectively, the workshop brought together programme managers, workstream leads, and partners from Mastercard Foundation, SFA Foundation, the Pandemic Sciences Institute and a representative from the Africa Oxford Initiative.

 

The importance of MEAL to the Collaborative

The University of Ibadan’s College of Medicine Provost, Professor Temidayo O. Ogundiran officially welcomed participants to Lagos and delivered the keynote address at the workshop. In his speech, he highlighted the significance of the MEAL function to the success of the Collaborative’s work.

“I am informed that this onboarding workshop has been carefully put together to strengthen all seven EPSILONs and to equip you with the necessary tools and frameworks to track progress, document results, and define learning, plus engage other stakeholders meaningfully. A robust MEAL system is needed to ensure that interventions are timely, decisions are evidenced correctly, progress is measured, and our impact is sustained – it should be rooted in transparency, excellence and shared commitment to deliver on the goals of the Collaborative”, Prof. Ogundiran remarked.

Carol Nuga, Director of Impact at the Mastercard Foundation, highlighted the evolution of the Foundation’s work – from individual scholarships to institutional strengthening, workforce development, and network-building to increase social capital to achieve our shared goals. She emphasised that MEAL is central to realising impact, influencing ecosystems, and ensuring young people benefit from dignified and fulfilling career pathways.

Prof. T.O. Ogundiran (University of Ibadan), Dr Chinedu Ugwu (Redeemer's University) and Carol Nuga (Mastercard Foundation) delivering their addresses during the workshop's opening ceremony.
Prof. T.O. Ogundiran (University of Ibadan), Dr Chinedu Ugwu (Redeemer’s University) and Carol Nuga (Mastercard Foundation) delivering their addresses during the workshop’s opening ceremony.

Building shared understanding and operationalisation of the MEAL Function

Over the four-day workshop, participants explored the structure of the Collaborative, the role of MEAL as a cross-cutting function, and the distinction between programme-level implementation by the EPSILONs and the overarching strategy led through wrap-around activities. Sessions reflecting on the Collaborative’s Theory of Change prompted deep discussion on accountability, influence, contextual differences and how MEAL can capture progress in real time.

The workshop also surfaced operational realities – from language diversity and bureaucratic constraints to the need for clear data responsibilities and integrated reporting systems. Demonstrations of the Collaborative’s MEAL tool helped teams understand how indicators, dashboards and learning inputs will be managed across institutions.

A panel on research-to-policy influence underscored the importance of trust, evidence synthesis, and science communication – key capabilities the Collaborative aims to strengthen across EPSILON teams. Additional sessions focused on impact storytelling, responsible communication, and the role of MEAL in shaping narratives of change.

Days three and four focused on translating principles into practice. Teams reviewed indicators at EPSILON and Collaborative levels, explored data flow and responsibilities, and discussed the MEAL tool that will support real-time reporting and learning.

By the final day, participants revisited the Collaborative’s Theory of Change with new clarity, refining their contributions and areas of influence. The workshop closed with a shared commitment to co-creation, continuous learning, and to building MEAL systems that reflect African contexts and strengthen pandemic readiness.

“This meeting has been engaging and packed with a lot of information. But most importantly, it has been useful in clarifying a lot of things, especially at the beginning of our work in the consortia, before activities kick-off and we need to change tack mid-way. I am grateful for this opportunity and go away with a better understanding of what lies ahead of us,” said Purity Wambui, a Programme Lead from the CLEAR-Africa consortium.

(Left) Montage Diallo responds to a question during the research-to-policy panel session. (Right) Wandaogo Haiga and Charles Guissou presenting the MOSEPIC's Theory of Change
(Left) Montage Diallo responds to a question during the research-to-policy panel session. (Right) Wandaogo Haiga and Charles Guissou presenting the MOSEPIC’s Theory of Change

Looking Ahead

Across four days, one message rang consistently: this Collaborative is an opportunity to build something transformative – not only for institutions, but for African health systems, scientific ecosystems, and future generations of researchers and policymakers.

The MEAL onboarding workshop did more than align frameworks. It built trust. It clarified roles. It surfaced the complexity and promise of working across contexts, disciplines and expectations. And it reminded participants that the strength of the Collaborative lies in the people driving it.

“Having missed the inception meeting in Nairobi, I am grateful for the opportunity to be a part of this workshop. Before this, I was very confused about the whole Collaborative and how it works. I also had a limited scope to the objectives and goals of the programme. But now, I have a big picture view of what we are trying to do, and how everything fits in together,” said Dr Chinedu Ugwu, a co-lead from the SPIL-OVA consortium.

Together, the Collaborative is laying the groundwork for rigorous science, stronger systems, and evidence that genuinely shapes Africa’s readiness for future epidemics and pandemics.

Participants from the MEAL onboarding workshop pose for a group photo with the Provost (College of Medicine, University of Ibadan) Prof T.O. Ogundiran and Carol Nuga, the Director of Impact, Mastercard Foundation
Participants from the MEAL onboarding workshop pose for a group photo with the Provost (College of Medicine, University of Ibadan) Prof T.O. Ogundiran and Carol Nuga, the Director of Impact, Mastercard Foundation
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